Bdron tablets contain the active ingredient abiraterone acetate, which is a type of medicine known an androgen biosynthesis inhibitor or an anti-androgen. (Androgens are male sex hormones such as testosterone.) Bdron is used in the treatment of prostate cancer that has spread beyond the prostate gland. Standard treatment for prostate cancer that has spread beyond the prostate gland involves stopping the production of testosterone by the testicles, in order to slow the growth of the cancer cells. This is usually acheived with medicines called LHRH or gonadorelin analogues, or with surgery to the testicles. However, for some men this treatment does not work.
Abiraterone is used for prostate cancers that are resistant to medical or surgical castration. It works by preventing the action of an enzyme called cytochrome P17, which is also involved in the production of testosterone. This enzyme is found in the testicles, the adrenal glands and the tissues of the prostate tumour. By inhibiting the activity of this enzyme in all these places, the amount of testosterone in the body is decreased more than by medical or surgical castration. This helps to reduce the growth of the prostate cancer cells.
How Bdron can help?
Prostate cancer that has spread to other parts of the body. Treatment with Bdron is used for men whose cancer is resistant to medical or surgical castration. It may be used before chemotherapy, or for cancer that has progressed on or after a chemotherapy regimen containing docetaxel. Men having treatment with an LHRH analogue should continue this treatment as well as taking Bdron. It is used in combination with a steroid medicine called prednisone or prednisolone. The steroid is given to reduce the chances of fluid retention, raised blood pressure or a drop in the level of potassium in your blood as a result of the Bdron treatment.