Exemptia 40 mg
₹ 5,500.00₹ 12,000.00
Exemptia 40 MG/0.8 ML
Generic Name: Adalimumab
Zydus Lifesciences Ltd
Exemptia 40 mg Injection contains Adalimumab, a biological medicine that belongs to a group of medicines called tumour necrosis factor (TNF) blockers.
Description
Exemptia 40 mg Injection (Adalimumab)
Exemptia 40 mg Injection contains Adalimumab, a biological medicine that belongs to a group of medicines called tumour necrosis factor (TNF) blockers. Adalimumab helps reduce excessive inflammation by blocking the action of TNF, a protein involved in the body’s inflammatory response. Exemptia is used to treat several autoimmune and inflammatory conditions when prescribed by a specialist.
Each Exemptia 40 mg Injection contains 40 mg of Adalimumab and is administered by subcutaneous injection. Depending on the condition, patients may receive Exemptia on a regular schedule after an initial loading dose.
Uses of Exemptia 40 mg Injection
Rheumatoid Arthritis
Exemptia is used to treat moderate to severe rheumatoid arthritis. Adalimumab helps reduce inflammation in the joints, relieve symptoms, and slow the progression of joint damage. It may be used alone or together with other medicines such as methotrexate.
Psoriatic Arthritis
Adalimumab can help control psoriatic arthritis, an inflammatory condition associated with psoriasis. Exemptia may reduce joint pain, swelling, stiffness, and other symptoms.
Ankylosing Spondylitis
Exemptia may be prescribed for ankylosing spondylitis, a chronic inflammatory condition affecting the spine and other joints. Adalimumab helps reduce inflammation and improve mobility.
Plaque Psoriasis
Adalimumab is used to treat moderate to severe chronic plaque psoriasis in appropriate patients. It can help reduce the thickness, scaling, redness, and extent of psoriasis lesions.
Crohn’s Disease and Ulcerative Colitis
Exemptia may be used to treat moderate to severe Crohn’s disease and ulcerative colitis. By blocking TNF, Adalimumab can reduce intestinal inflammation and help control symptoms.
Therapeutic Effects of Exemptia
How Adalimumab Works
Adalimumab is a monoclonal antibody that specifically binds to TNF-alpha. TNF-alpha plays an important role in causing and maintaining inflammation in several autoimmune diseases. By blocking TNF-alpha, Adalimumab reduces excessive inflammatory activity.
Treatment Benefits
Exemptia can help reduce pain, swelling, stiffness, skin inflammation, and other symptoms associated with inflammatory diseases. In some conditions, continued Adalimumab treatment can also help maintain remission and reduce disease progression.
Interaction with Other Drugs
Immunosuppressive Medicines
Tell your doctor about all medicines you take before starting Exemptia. Combining Adalimumab with certain biological medicines or other potent immunosuppressants may increase the risk of serious infections.
Live Vaccines
Avoid live vaccines while receiving Exemptia unless your doctor specifically recommends otherwise. Adalimumab suppresses part of the immune system and may affect the body’s ability to respond safely to live vaccines.
Other Medicines
Inform your doctor about prescription medicines, over-the-counter medicines, vitamins, and herbal supplements. Your doctor will check for possible interactions before starting Adalimumab.
More Information About Exemptia
Strength and Form
Exemptia 40 mg Injection contains 40 mg of Adalimumab for subcutaneous administration. It is supplied as a prefilled injection or device according to the available product presentation.
Storage
Store Exemptia in a refrigerator at 2°C to 8°C. Do not freeze the injection. Keep it in the original packaging and protect it from light. If required, follow the manufacturer’s instructions regarding temporary storage outside the refrigerator.
How to Administer Exemptia
Recommended Dose
The dose and treatment schedule of Exemptia depend on the condition being treated. For many adult inflammatory conditions, 40 mg of Adalimumab is administered every other week, although some conditions require a different initial or maintenance schedule. Your doctor will determine the appropriate dose.
Method of Administration
Exemptia is given as a subcutaneous injection, usually into the abdomen or thigh. Rotate injection sites to reduce irritation. Do not inject into areas that are bruised, red, hard, tender, or affected by psoriasis.
Missed Dose
If you miss an Exemptia dose, administer it as soon as you remember and then follow your original treatment schedule unless your doctor provides different instructions. Do not take an extra dose to compensate for a missed injection.
Safety Advice
Breastfeeding
Adalimumab can pass into breast milk in small amounts. If you are breastfeeding or planning to breastfeed, discuss the benefits and potential risks of Exemptia treatment with your doctor before continuing therapy.
Alcohol
There is no specific requirement to completely avoid alcohol with Adalimumab, but excessive alcohol consumption may affect overall health and can increase the risk of liver problems, particularly when other medicines are also being used. Follow your doctor’s advice.
Liver
Tell your doctor if you have liver disease or a history of hepatitis. Adalimumab can rarely cause liver problems and may reactivate hepatitis B in people who have previously been infected. Your doctor may perform appropriate screening and monitoring before and during treatment.
Kidney
Inform your doctor if you have kidney disease or other significant medical conditions. Your doctor will consider your overall health before starting Exemptia.
Lungs
Adalimumab can increase the risk of serious infections, including tuberculosis and other respiratory infections. Tell your doctor if you have a persistent cough, fever, night sweats, unexplained weight loss, or breathing difficulties. Tuberculosis screening is generally required before starting treatment.
Driving
Exemptia does not usually affect the ability to drive. However, if you experience dizziness, weakness, or other symptoms that affect your alertness, avoid driving or operating machinery until you feel better.
Pregnancy
If you are pregnant, planning to become pregnant, or think you may be pregnant, inform your doctor before using Exemptia. Adalimumab may use during pregnancy in certain situations when the expect benefits outweigh potential risks. Your doctor will determine whether treatment should continue.
Side Effects of Exemptia
Common Side Effects
Possible side effects of Exemptia include:
- Injection-site reactions
- Headache
- Nausea
- Abdominal pain
- Upper respiratory tract infections
- Sinusitis
- Back pain
- Rash
- Increased susceptibility to infections
Serious Side Effects
Adalimumab can increase the risk of serious infections, including tuberculosis, bacterial infections, fungal infections, and opportunistic infections. Rarely, treatment may also associate with serious allergic reactions, hepatitis B reactivation, blood disorders, neurological disorders, or worsening heart failure.
When to Contact Your Doctor
Contact your doctor immediately if you develop persistent fever, severe cough, difficulty breathing, unusual bruising or bleeding, yellowing of the skin or eyes, severe weakness, swelling of the face or throat, or other signs of a serious infection or allergic reaction.
Word of Advice
Exemptia 40 mg Injection containing Adalimumab is a prescription biological medicine that should use under the supervision of a qualified healthcare professional. Your doctor may perform screening for tuberculosis and hepatitis B before treatment and monitor you for infections during therapy. Do not stop Adalimumab or change the injection schedule without medical advice. Follow proper injection and storage instructions to maintain the effectiveness and safety of Exemptia.
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