Empaveli 1080Mg Injection

₹ 0.00~~₹ 0.00~~

Brand: Empaveli

Generic: Pegcetacoplan

Manufacturer: Apellis Pharmaceuticals

Drug class: Complement inhibitor (specifically targeting complement protein C3).

Description

Introduction to Empaveli 1080mg Injection

Empaveli 1080mg Injection contains pegcetacoplan as its active ingredient and is developed by Apellis Pharmaceuticals, Inc. It is used to treat adults with paroxysmal nocturnal haemoglobinuria (PNH), a rare blood disorder that can cause the destruction of red blood cells, blood clots, and problems with the bone marrow.

Empaveli is a complement C3 inhibitor that helps control the body’s complement system, which can damage red blood cells in people with PNH. Pegcetacoplan binds to a protein called C3 and blocks its activity. This helps reduce the destruction of red blood cells both inside and outside the blood vessels.

By reducing red blood cell destruction, Empaveli can help improve haemoglobin levels and reduce the need for blood transfusions. It is usually given twice a week as a subcutaneous infusion (under the skin). After proper training, some patients may be able to administer the medicine at home as advised by their healthcare provider.

Uses Empaveli 1080mg Injection

Empaveli 1080mg Injection is used for:

Treating paroxysmal nocturnal haemoglobinuria (PNH) in adults by reducing the breakdown of red blood cells and helping improve haemoglobin levels.
Treating PNH in patients who remain anaemic despite previous treatment with C5 inhibitors, such as eculizumab or ravulizumab.
Reducing the need for blood transfusions in PNH by controlling the breakdown of red blood cells both inside and outside blood vessels.

Storage

Store Empaveli 1080mg Injection in a refrigerator at 2°C to 8°C.
Do not freeze the prefilled cartridge.
Before use, allow the medicine to come to room temperature for about 20–25 minutes.
Keep it in the original carton to protect it from light.
Keep the medicine out of the reach of children.

Safety Advice

Pregnancy

Consult Your Doctor

The safety of Empaveli during pregnancy is not known. If you are pregnant or planning to become pregnant, talk to your doctor before starting treatment.

Breastfeeding

Consult Your Doctor

It is not known if pegcetacoplan passes into breast milk. Talk to your doctor about the possible risks before breastfeeding while using Empaveli.

Lungs

Consult Your Doctor

Lung-related side effects are uncommon. However, tell your doctor immediately if you develop a new or worsening cough, shortness of breath, chest pain, or difficulty breathing.

Liver

Consult Your Doctor

Tell your doctor if you have any liver problems before starting Empaveli. Your doctor may recommend regular monitoring during treatment.

Alcohol

Consult Your Doctor

Talk to your doctor about drinking alcohol while using Empaveli. Alcohol may affect the immune system and may not be suitable for people with complement-mediated diseases.

Driving

Consult Your Doctor

Empaveli is not expected to affect your ability to drive. However, fatigue caused by PNH or its treatment may reduce alertness. Talk to your doctor if you feel tired or less alert.