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Soliris 300Mg Injection

₹ 0.00₹ 0.00

Brand: Soliris

Generic: Eculizumab

Manufacturer: Alexion Pharmaceuticals

Drug class: Monoclonal antibody and acts specifically as a complement inhibitor.

Description

Introduction to Soliris 300mg Injection

Soliris 300mg Injection contains eculizumab, a medicine that blocks a part of the immune system called the complement protein C5. It is mainly used to treat certain rare diseases, including paroxysmal nocturnal hemoglobinuria (PNH), atypical hemolytic uremic syndrome (aHUS), and generalised myasthenia gravis (gMG).

Soliris helps control excessive activity of the complement system. In PNH, it helps protect red blood cells from being destroyed. In aHUS, it helps reduce complement-related damage to the kidneys and other organs. In gMG, it can help reduce muscle weakness in appropriate patients.

The price of Soliris 300mg Injection may vary depending on the pharmacy, location, and pack size. Always purchase this medicine from a reliable and authorised pharmacy to ensure its quality and proper storage.

Uses of Soliris 300mg Injection

Soliris 300mg Injection is used to treat certain conditions caused by abnormal activation of the complement system.

• Paroxysmal Nocturnal Hemoglobinuria (PNH): Helps prevent the destruction of red blood cells and may reduce complications such as anaemia and blood clots.
• Atypical Hemolytic Uremic Syndrome (aHUS): Helps control abnormal complement activity and reduce damage to the kidneys and other organs.
• Generalised Myasthenia Gravis (gMG): Helps reduce muscle weakness in certain patients with this autoimmune condition.
• Complement-Mediated Conditions: Your doctor may prescribe eculizumab for other approved conditions where excessive complement activity plays an important role.

Use Soliris only when prescribed by your doctor. The appropriate treatment depends on your condition and medical history.

How Soliris 300mg Injection Works

Soliris 300mg Injection contains eculizumab, which blocks the C5 protein of the complement system.

The complement system normally helps the immune system fight infections. In some diseases, however, it becomes overactive and can damage healthy cells and tissues.

By blocking C5, Soliris helps reduce this harmful complement activity. In PNH, this can protect red blood cells from destruction. In aHUS, it can help reduce complement-related damage to the kidneys and other organs. In certain patients with gMG, it can help reduce the immune-related damage that contributes to muscle weakness.

Interaction of Soliris 300mg Injection with Other Medicines

Tell your doctor about all medicines you are taking before starting Soliris 300mg Injection. This includes prescription medicines, over-the-counter medicines, vitamins, supplements, and herbal products.

Your doctor will review your medicines and medical history to make sure Soliris is appropriate for you. Do not start, stop, or change any medicine without consulting your healthcare professional.

Storage Conditions

• Store Soliris 300mg Injection in a refrigerator at 2°C to 8°C (36°F to 46°F).
• Keep the medicine in its original carton to protect it from light.
• Do not freeze Soliris.
• Do not shake the vial.
• Keep it out of the reach of children.
• Follow the storage instructions provided with the product and by your healthcare professional.

Soliris should be handled and prepared by a qualified healthcare professional.

How to Take Soliris 300mg Injection

Soliris 300mg Injection is given through an intravenous (IV) infusion by a healthcare professional. The dose and treatment schedule depend on the condition being treated.

Do not try to inject Soliris yourself. Your doctor will determine the correct dose and infusion schedule for you.

You may be monitored during and after the infusion for any signs of an infusion-related reaction. Regular medical check-ups and laboratory tests may also be required during treatment.

Do not miss scheduled doses or stop treatment without speaking with your doctor.

Safety Advices

Pregnancy

Consult Your Doctor

Tell your doctor if you are pregnant, planning to become pregnant, or think you may be pregnant. Your doctor will consider the potential benefits and risks of treatment before recommending Soliris during pregnancy.

Breastfeeding

Consult Your Doctor

Tell your doctor if you are breastfeeding or planning to breastfeed. Your doctor will advise whether breastfeeding is appropriate while receiving Soliris based on your individual circumstances.

Lungs

Consult Your Doctor

Tell your doctor about any breathing problems or serious infections before receiving Soliris. Seek medical attention if you develop difficulty breathing, chest pain, or other severe respiratory symptoms during treatment.

Liver

Consult Your Doctor

Tell your doctor if you have liver disease or any other serious medical condition before starting treatment. Your doctor will decide whether any additional monitoring is required.

Alcohol

Consult Your Doctor

There is no specific general prohibition on alcohol with Soliris. However, because you are receiving treatment for a serious medical condition, discuss alcohol consumption with your doctor, particularly if you take other medicines or have liver or other health problems.

Driving

Consult Your Doctor

Soliris does not normally require patients to avoid driving. However, if you experience dizziness, weakness, or another symptom that affects your ability to drive safely, avoid driving or operating machinery and consult your doctor.

Side Effects

Like all medicines, Soliris 300mg Injection may cause side effects, although not everyone experiences them.

Common Side Effects

Some commonly reported side effects may include:

• Headache
• Nasopharyngitis or cold-like symptoms
• Back pain
• Nausea
• Diarrhea
• Fatigue
• Cough
• Dizziness
• Muscle or joint pain
• Other symptoms related to the underlying condition or treatment

The side effects you experience may vary depending on your medical condition and other medicines you are receiving.

Serious Side Effects

Soliris can increase the risk of certain serious infections, particularly meningococcal infection. Contact your doctor immediately if you develop symptoms such as:

• Sudden fever
• Severe headache
• Stiff neck
• Nausea or vomiting
• Confusion
• Sensitivity to light
• Severe weakness

Serious allergic or infusion-related reactions can also occur. Tell your healthcare professional immediately if you experience difficulty breathing, swelling, severe rash, chest discomfort, or a sudden drop in blood pressure during or after the infusion.

Important Safety Information

Because Soliris blocks part of the immune system, it can increase the risk of serious infections. Meningococcal vaccination is required before starting treatment in most cases, unless urgent treatment is medically necessary. Your doctor may also recommend additional precautions or antibiotics depending on your situation.

Seek urgent medical attention if you develop signs of a serious infection during treatment.

Expert Tips

• Take Soliris exactly as prescribed by your doctor.
• Do not miss scheduled infusion appointments.
• Make sure your doctor knows about all your medicines and supplements.
• Follow your doctor’s vaccination recommendations before and during treatment.
• Immediately report fever, severe headache, stiff neck, confusion, breathing problems, or other signs of serious infection.
• Do not stop Soliris treatment without speaking with your doctor.
• Attend all recommended follow-up appointments and laboratory tests.
• Store Soliris exactly as directed and do not freeze or shake the vial.
• Always receive Soliris under the supervision of a qualified healthcare professional.